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Gary Piazza Selected Research

sulindac sulfone (exisulind)

5/2004Combinatorial chemoprevention: efficacy of lovostatin and exisulind on the formation and progression of aberrant crypt foci.
9/2003Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells.
5/2003Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival.
3/2002Exisulind in combination with docetaxel inhibits growth and metastasis of human lung cancer and prolongs survival in athymic nude rats with orthotopic lung tumors.
2/2002Preclinical and clinical studies of docetaxel and exisulind in the treatment of human lung cancer.

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Gary Piazza Research Topics

Disease

3Neoplasms (Cancer)
09/2003 - 03/2002
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2003 - 02/2002
2Adenoma (Adenomas)
09/2015 - 09/2003
2Lung Neoplasms (Lung Cancer)
03/2002 - 02/2002
1Aberrant Crypt Foci
05/2004
1Colonic Neoplasms (Colon Cancer)
09/2003
1Neoplasm Metastasis (Metastasis)
03/2002
1Polyps
02/2002
1Colorectal Neoplasms (Colorectal Cancer)
02/2002

Drug/Important Bio-Agent (IBA)

5sulindac sulfone (exisulind)IBA
05/2004 - 02/2002
3Docetaxel (Taxotere)FDA Link
05/2003 - 02/2002
2Sulindac (Copal)FDA LinkGeneric
09/2003 - 03/2002
2Cyclic GMPIBA
05/2003 - 03/2002
2Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
05/2003 - 03/2002
1fibroblast growth factor 18IBA
09/2015
1CarcinogensIBA
05/2004
1sulindac sulfideIBA
09/2003
1Proteins (Proteins, Gene)FDA Link
09/2003
1CaspasesIBA
09/2003
1Proteasome Endopeptidase Complex (Proteasome)IBA
09/2003
1beta CateninIBA
09/2003
1Protein Isoforms (Isoforms)IBA
05/2003
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
03/2002
1SulfonesIBA
03/2002
1EnzymesIBA
03/2002
1taxaneIBA
03/2002
1Antineoplastic Agents (Antineoplastics)IBA
02/2002

Therapy/Procedure

2Chemoprevention
05/2004 - 02/2002
1Therapeutics
05/2004
1Aftercare (After-Treatment)
05/2003
1Drug Therapy (Chemotherapy)
02/2002